Answer
Maribavir is metabolised primarily by hepatic CYP3A4 (estimated fraction ≥35%), with secondary CYP1A2 involvement (≤25%); UGT1A1, UGT1A3, UGT2B7 and possibly UGT1A9 mediate glucuronidation, which contributes little to overall clearance based on in vitro data.
Sources for this answer
- LIVTENCITY 200 mg film coated tabletsTakeda UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 5Document updated
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