How does maribavir inhibit cytomegalovirus replication?

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Maribavir competitively blocks ATP binding to the viral UL97 serine/threonine protein kinase during viral DNA replication, inhibiting phosphotransferase activity and cytomegalovirus DNA replication, maturation, encapsidation and nuclear egress without affecting concatemer maturation.

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LIVTENCITY 200 mg film coated tabletsTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 5Document updated 26 June 2025

Sources checked 8 November 2026

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