Answer
In vitro studies suggest that CYP3A4 and CYP2B6 are the main enzymes responsible for metabolising the efavirenz component of efavirenz/emtricitabine/tenofovir disoproxil maleate.
Sources for this answer
- Efavirenz/Emtricitabine/Tenofovir Disoproxil 600 mg/200 mg/245 mg Film-coated TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §5.2 Pharmacokinetic properties · Version 17Document updated
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