Answer
The mean elimination half-life of Defitelio (defibrotide) was 0.71 hours (SD 0.35 hours) in 52 healthy volunteers after a single 6.25 mg/kg intravenous infusion over two hours.
Sources for this answer
- Defitelio 80 mg/mL concentrate for solution for infusionJazz Pharmaceuticals UK Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 14Document updated
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