Answer
Taking imipramine hydrochloride with buprenorphine increases the risk of potentially life-threatening serotonin syndrome, so the combination requires caution.
Sources for this answer
- Imipramine Hydrochloride 25mg/5ml Oral SolutionEssential Pharma Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated
Sources checked