Answer
Ventricular arrhythmia, ventricular fibrillation, sudden cardiovascular collapse and death have been reported with high systemic concentrations of bupivacaine hydrochloride.
Sources for this answer
- Bupivacaine Hydrochloride 0.5% w/v solution for injectionAspen · emc · SmPC §4.4 Special warnings and precautions for use · Version 7Document updated
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