Answer
Icatibant acetate should be administered cautiously in patients with acute ischaemic heart disease or unstable angina because bradykinin type 2 receptor antagonism could theoretically worsen cardiac function and decrease coronary blood flow under ischaemic conditions.
Sources for this answer
- Icatibant 30 mg solution for injection in pre-filled syringePiramal Critical Care Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 1Document updated
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