Answer
Icatibant acetate is extensively metabolised by proteolytic enzymes into inactive metabolites primarily excreted in urine, with less than 10% of the dose eliminated in urine as unchanged drug.
Sources for this answer
- Icatibant 30 mg solution for injection in pre-filled syringePiramal Critical Care Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 1Document updated
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