nortriptyline hydrochloride · Medicine question

What potentially life-threatening condition can occur when nortriptyline hydrochloride is taken with buprenorphine?

Name: What potentially life-threatening condition can occur when nortriptyline hydrochloride is taken with buprenorphine?
Published: 2026-11-08T14:24:28.959Z

iatroX medicinesPublished 8 November 2026

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Taking nortriptyline hydrochloride with buprenorphine may cause serotonin syndrome, a potentially life-threatening condition.

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Nortriptyline 10mg Film-coated TabletsGlenmark Pharmaceuticals Europe Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 5Document updated 14 February 2024

Sources checked 8 November 2026

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