Answer
Risdiplam may compromise male fertility during treatment, with sperm degeneration and reduced sperm numbers observed in rats and monkeys; based on animal studies, effects on sperm cells are expected to reverse after discontinuation.
Sources for this answer
- Evrysdi 0.75 mg/mL powder for oral solutionRoche Products Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 13Document updated
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