methotrexate · Medicine question

What physical incompatibility can occur when the Hospira UK Ltd methotrexate 25 mg/ml injection product is mixed with certain concentrations of heparin sodium in a syringe?

iatroX medicinesPublished 8 November 2026

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The Hospira UK Ltd methotrexate 25 mg/ml injection product produces immediate precipitation or turbidity when mixed with certain concentrations of heparin sodium in a syringe.

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Methotrexate 25 mg/ml InjectionHospira UK Ltd · emc · SmPC §6.2 Incompatibilities · Version 28Document updated 7 September 2026

Sources checked 8 November 2026

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