ranolazine · Medicine question

What muscle-related adverse effect has been reported with ranolazine and simvastatin taken together?

Name: What muscle-related adverse effect has been reported with ranolazine and simvastatin taken together?
Published: 2026-11-08T02:01:29.006Z

iatroX medicinesPublished 8 November 2026

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Rhabdomyolysis has been reported during postmarketing use in patients taking ranolazine (Ranexa) and simvastatin together.

Sources for this answer

Ranexa 375 mg Prolonged-release tabletA. Menarini Farmaceutica Internazionale SRL · emc · SmPC §4.5 Interaction with other medicinal products · Version 20Document updated 21 April 2023

Sources checked 8 November 2026

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