skip to main content

brainstorm askiatroX medicines

simulations beta

loading page…

learn & practise

exams international doctors free questions Socratic Tutor rounds stat clinical connections academy journal tool guides

clinical reference

askiatroX knowledge centre medicines UK / NICE guidance international guidance calculators q&a library

trust & support

how it works methodology account & support frequently asked questions about us clinical safety consultancy

legal

mobile app · scan to download

Medicines pembrolizumabQuestion & answer

pembrolizumab · Medicine question

What is the terminal half-life of pembrolizumab at steady state?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Pembrolizumab has a geometric mean terminal half-life of 22 days at steady state, with a coefficient of variation of 32%.

Sources for this answer

KEYTRUDA 25 mg/mL concentrate for solution for infusionMerck Sharp & Dohme (UK) Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 67Document updated 14 October 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

The full medicine guide

More questions about pembrolizumab

What is the shelf life of an unopened vial of Keytruda (pembrolizumab) 25 mg/mL concentrate for solution for infusion?Are clinical data available on the effects of pembrolizumab on fertility?Are metabolic drug–drug interactions expected with pembrolizumab?Can pembrolizumab cause immune-mediated pneumonitis?Can pembrolizumab cause inflammation of the kidneys (immune-mediated nephritis)?Can pembrolizumab cause type 1 diabetes with ketoacidosis?

pembrolizumab

Read the wider context, including uses, precautions and the sources behind this medicine guide.

Read the pembrolizumab guide

More clinical questions?

Explore the tools and reference material available on iatroX.

Explore askiatroX