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Medicines pembrolizumabQuestion & answer

pembrolizumab · Medicine question

Can pembrolizumab cause type 1 diabetes with ketoacidosis?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, type 1 diabetes associated with ketoacidosis is listed as an immune-mediated adverse reaction to Keytruda (pembrolizumab).

Sources for this answer

KEYTRUDA 25 mg/mL concentrate for solution for infusionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.2 Posology and method of administration · Version 64Document updated 14 May 2026

Sources checked 8 November 2026

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