What is Protopic 0.1% tacrolimus ointment used to treat in adults and adolescents aged 16 years and over?

Protopic 0.1% tacrolimus ointment treats moderate-to-severe atopic dermatitis in people aged ≥16 when conventional therapies fail or are intolerable, and prevents flares/prolongs flare-free intervals in those with ≥4 exacerbations/year whose lesions cleared, almost cleared or became mildly affected after up to six weeks of twice-daily tacrolimus.