darolutamide · Medicine question

What is known about darolutamide's effect on male fertility?

iatroX medicinesPublished 8 November 2026

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There are no human data on darolutamide's effect on fertility, but animal studies indicate that Nubeqa (darolutamide) may impair fertility in males of reproductive potential.

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NUBEQA 300 mg film coated tabletsBayer plc · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 10Document updated 10 June 2025

Sources checked 8 November 2026

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Can darolutamide harm an unborn baby?Does Nubeqa (darolutamide) affect the ability to drive or use machines?How common were fatigue and asthenic conditions in patients receiving darolutamide in the pooled ARAMIS and ARANOTE studies?How does darolutamide affect exposure to rosuvastatin?How does darolutamide block androgen receptor signalling?How much lactose monohydrate does each Nubeqa (darolutamide) 300 mg film-coated tablet contain?

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