Answer
Binimetinib is an ATP-uncompetitive, reversible inhibitor of MEK1 and MEK2 kinase activity that also inhibits MEK activation by BRAF, targeting the ERK pathway that promotes cellular proliferation.
Sources for this answer
- Mektovi 15 mg film-coated tabletsPierre Fabre Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 10Document updated
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