skip to main content

brainstorm askiatroX medicines

simulations beta

loading page…

learn & practise

exams international doctors free questions Socratic Tutor rounds stat clinical connections academy journal tool guides

clinical reference

askiatroX knowledge centre medicines UK / NICE guidance international guidance calculators q&a library

trust & support

how it works methodology account & support frequently asked questions about us clinical safety consultancy

legal

mobile app · scan to download

Medicines binimetinibQuestion & answer

binimetinib · Medicine question

How can St John's wort affect binimetinib exposure?

iatroX medicinesPublished 8 November 2026

The answer

Answer

St John's wort induces Pgp transport and may decrease binimetinib exposure, potentially reducing its efficacy.

Sources for this answer

Mektovi 15 mg film-coated tabletsPierre Fabre Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 9Document updated 2 January 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

The full medicine guide

binimetinib

More questions about binimetinib

Can binimetinib cause high blood pressure or worsen existing hypertension?Can Mektovi (binimetinib) tablets be taken with or without food?How much lactose monohydrate does each Mektovi 15 mg binimetinib film-coated tablet contain?Is binimetinib recommended during pregnancy?What precautions apply to driving or using machines while taking binimetinib?Which adults with melanoma are eligible for binimetinib in combination with encorafenib?

Read the wider context, including uses, precautions and the sources behind this medicine guide.

Read the binimetinib guide

More clinical questions?

Explore the tools and reference material available on iatroX.

Explore askiatroX