Answer
Bedaquiline taken with clofazimine is expected to have an additive effect on QT prolongation, so Sirturo treatment may be considered only after a favourable benefit-risk assessment and with ECG monitoring.
Sources for this answer
- Sirturo 100 mg tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.4 Special warnings and precautions for use · Version 21Document updated
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