Answer
Short-term co-administration of ketoconazole, a strong CYP3A4 inhibitor, increased mean bedaquiline exposure (AUC) by 22% in healthy adults (90% confidence interval: 12%–32%).
Sources for this answer
- Sirturo 100 mg tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.5 Interaction with other medicinal products · Version 21Document updated
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