Answer
Combining vortioxetine hydrobromide with tramadol may lead to serotonin syndrome, and caution is also advised because both can lower the seizure threshold.
Sources for this answer
- Brintellix 5mg, 10mg and 20mg tablets (15mg not marketed)Lundbeck Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 19Document updated
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