Answer
In healthy subjects, bupropion 150 mg twice daily, a strong CYP2D6 inhibitor, increased vortioxetine hydrobromide exposure (AUC) 2.3-fold when co-administered with vortioxetine 10 mg/day for 14 days.
Sources for this answer
- Brintellix 5mg, 10mg and 20mg tablets (15mg not marketed)Lundbeck Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 19Document updated
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