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Medicines metolazoneQuestion & answer

metolazone · Medicine question

What interaction can occur between metolazone and lithium?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Taking metolazone with lithium may reduce lithium clearance, leading to lithium intoxication.

Sources for this answer

Xaqua 5 mg TabletsRenascience Pharma Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated 5 August 2025

Sources checked 8 November 2026

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The full medicine guide

metolazone

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