Answer
When nonacog beta pegol (Refixia) is activated, the activation peptide containing the 40 kDa polyethylene glycol component is cleaved off, leaving the native activated factor IX molecule.
Sources for this answer
- Refixia 500 IU powder and solvent for solution for injectionNovo Nordisk Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated
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