Answer
With avapritinib in unresectable or metastatic GIST, fluid retention includes facial, periorbital and peripheral oedema, pleural effusion, generalised oedema and ascites (at least common, including severe cases), plus laryngeal oedema and pericardial effusion (uncommon).
Sources for this answer
- AYVAKYT 300 mg film-coated tabletsBlueprint Medicines (Netherlands) B.V. · emc · SmPC §4.4 Special warnings and precautions for use · Version 3Document updated
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