Answer
When administered as Vyxeos liposomal, the plasma half-lives of total (encapsulated plus unencapsulated) daunorubicin and cytarabine are 31.5 hours (CV 28.5%) and 40.4 hours (CV 24.2%), respectively, with over 99% of both drugs remaining encapsulated within liposomes in plasma.
Sources for this answer
- VyxeosJazz Pharmaceuticals UK Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 15Document updated
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