What are the most common adverse reactions reported with crovalimab in patients with paroxysmal nocturnal haemoglobinuria?

The most common crovalimab adverse reactions in paroxysmal nocturnal haemoglobinuria were Type III immune complex mediated reaction (18.9%, in patients switching from another C5 inhibitor), upper respiratory tract infection (18.6%), pyrexia (13.5%), headache (10.9%) and infusion-related reaction (10.2%).