Answer
Following a single 400 mg oral dose of radiolabelled sofosbuvir, the median terminal half-lives of sofosbuvir and its metabolite GS-331007 were 0.4 hours and 27 hours, respectively.
Sources for this answer
- Sovaldi 400 mg film-coated tabletsGilead Sciences Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 4Document updated
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