Answer
After a single 25 mg intravenous dose of temsirolimus in patients with cancer, the mean half-lives of temsirolimus and its metabolite sirolimus are 17.7 hours and 73.3 hours, respectively.
Sources for this answer
- TORISEL 30 mg concentrate and solvent for solution for infusionPfizer Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 33Document updated
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