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What is the current first-line eradication therapy for H. pylori in the UK, and how long should it be administered?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

The current first-line eradication therapy for Helicobacter pylori infection in the UK is a 7-day, twice-daily course of a proton pump inhibitor (PPI) combined with amoxicillin and either clarithromycin or metronidazole 1.

The recommended duration of treatment is 7 days 1.

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