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first line hrt in woman with previous histerectomy

Clinical answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP.

Posted: 29 July 2025Updated: 29 July 2025 Clinically Reviewed

For a woman who has had a previous hysterectomy, the first-line hormone replacement therapy (HRT) is oestrogen-only preparation, such as oral or transdermal oestrogen.

Educational content only. Always verify information and use clinical judgement.