Strongly suspected bacterial meningitis with a new focal neurological deficit — MRCEM SBA MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: D — Take blood cultures, give intravenous ceftriaxone and dexamethasone, perform CT head after stabilisation, then perform lumbar puncture once the weakness resolves.
Fever, headache, neck stiffness and confusion make bacterial meningitis strongly suspected. Her new focal weakness changes the usual investigation sequence: neuroimaging is indicated, and lumbar puncture must not be performed while that feature persists. Take blood samples, start intravenous ceftriaxone promptly and give intravenous dexamethasone with or before the first antibiotic dose if possible. Stabilise her before CT; reassess whether lumbar puncture is safe once the focal feature has resolved. Arrange senior, infection-specialist and appropriate inpatient assessment. ([nice.org.uk](https://www.nice.org.uk/guidance/ng240/chapter/Recommendations)) A correctly recognises the need for CT but delays treatment until after imaging. B applies the usual preference for pre-antibiotic lumbar puncture despite a current contraindicating feature. C correctly treats before imaging, but a CT showing no mass lesion does not, by itself, remove the requirement to wait for the focal sign to resolve. E delays dexamethasone until microbiological confirmation, although it is indicated when bacterial meningitis is strongly suspected; antibiotics should not, however, be delayed if dexamethasone is unavailable. ([nice.org.uk](https://www.nice.org.uk/guidance/ng240/chapter/Recommendations))
Reference: NICE NG240: Meningitis (bacterial) and meningococcal disease — recommendations (19 March 2024) — https://www.nice.org.uk/guidance/ng240/chapter/recommendations NICE NG240: Antibiotics and corticosteroids for bacterial meningitis (19 March 2024) — https://www.nice.org.uk/guidance/ng240/chapter/Recommendations