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Suspected ectopic pregnancy with intrauterine contraception in situ — DFSRH MCQ

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HardWarning SymptomsSuspected ectopic pregnancy with intrauterine contraception in situDFSRH

A 29-year-old woman presents to a community sexual and reproductive health clinic with 24 hours of left-sided pelvic pain and light vaginal bleeding. A 52 mg levonorgestrel intrauterine device was inserted 18 months ago. She has previously been amenorrhoeic but reports breast tenderness and nausea for 2 weeks. She is uncertain whether she would continue a pregnancy. Her pulse is 82 beats/min, blood pressure 118/72 mmHg and temperature 36.7°C. There is mild left lower-quadrant abdominal tenderness without guarding. Speculum examination confirms slight bleeding through a closed cervical os; the device threads are visible. Bimanual examination elicits left adnexal tenderness without cervical excitation. A urine pregnancy test is positive. Which is the most appropriate immediate management plan?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CRefer immediately to an early pregnancy assessment service for transvaginal ultrasonography, leaving the device undisturbed until pregnancy location is established

Explanation lettering: E = shown as A · C = shown as B · A = shown as C · B = shown as D · D = shown as E

Pregnancy is uncommon during intrauterine contraception, but when it occurs with a device in situ, the proportion that is ectopic is higher than among pregnancies conceived without intrauterine contraception. This patient has three warning features requiring immediate assessment: a positive pregnancy test, unilateral pelvic pain and abdominal/adnexal tenderness. Haemodynamic stability makes direct resuscitation-area transfer unnecessary, but NICE recommends immediate referral to an early pregnancy assessment service or out-of-hours gynaecology service in this presentation. Transvaginal ultrasonography should establish pregnancy location. The visible threads do not justify removing the device before localisation. FSRH recommends following the early pregnancy pathway first; if an intrauterine pregnancy under 12 weeks is subsequently confirmed, the device should usually be removed when its threads are visible or readily accessible, irrespective of whether the pregnancy will continue. B reverses this sequence and delays assessment of a possible ectopic pregnancy. C incorrectly uses serial hCG as a gatekeeper to imaging; hCG trends support management of a pregnancy of unknown location after specialist assessment but do not safely exclude ectopic pregnancy. D is unsupported by the positive pregnancy test, absent cervical excitation and lack of infective features. E recognises the need for imaging but routine timing is unsafe because pain with tenderness and a positive pregnancy test requires immediate referral.

Reference: FSRH Guideline: Intrauterine Contraception (March 2023; amended January 2025) — https://www.fsrh.org/Common/Uploaded%20files/documents/fsrh-clinical-guideline-intrauterine-contraception-mar-23-amended.pdf FSRH Guideline: Intrauterine Contraception (March 2023; amended January 2025) — https://www.fsrh.org/Common/Uploaded%20files/documents/fsrh-clinical-guideline-intrauterine-contraception-mar-23-amended.pdf NICE NG126: Symptoms and signs of ectopic pregnancy and initial assessment (17 June 2026) — https://www.nice.org.uk/guidance/NG126/chapter/symptoms-and-signs-of-ectopic-pregnancy-and-initial-assessment