Chronic urinary retention causing renal impairment, likely secondary to bladder outlet obstruction — MSRA MCQ
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Correct answer: E — Catheterise the bladder now and arrange urgent specialist assessment with upper urinary tract imaging
Explanation lettering: E = shown as A · A = shown as B · B = shown as C · C = shown as E
This is chronic urinary retention with clinically important renal impairment, most likely from bladder outlet obstruction due to benign prostatic enlargement. The decisive features are the very large post-void residual volume (1.25 L), a palpable-equivalent chronically overdistended bladder state with overflow symptoms, and a substantial creatinine rise from baseline. NICE recommends serum creatinine testing and upper urinary tract imaging in chronic retention when residual volume exceeds 1 L or the bladder is palpable/percussable. It also recommends catheterisation when renal impairment or hydronephrosis is secondary to chronic retention. Specialist assessment is indicated because LUTS are complicated by suspected renal impairment. A and B may be appropriate pharmacological approaches for uncomplicated bothersome LUTS, but neither provides the necessary immediate bladder drainage or addresses potential upper tract damage. D inappropriately delays decompression and investigation in a patient with renal dysfunction. E may be considered before long-term indwelling catheterisation in selected chronic retention, but immediate drainage is required here; the patient also needs urgent assessment of renal tract consequences rather than a delayed primary-care review.
Reference: NICE CG97: Lower urinary tract symptoms in men: management — Recommendations (Published 2010; last reviewed 19 December 2024) — https://www.nice.org.uk/guidance/cg97/chapter/recommendations