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Tramadol-associated delirium and constipation — SCE Geriatric Medicine MCQ

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HardPolypharmacyTramadol-associated delirium and constipationSCE Geriatric Medicine

An 89-year-old woman is admitted with severe back pain, reduced mobility and confusion after starting tramadol for vertebral fracture pain. Sodium is 128 mmol/L, creatinine is baseline, 4AT is 5 and she has not opened bowels for six days. What is the most appropriate management?

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Correct answer: DStop tramadol, treat constipation and delirium precipitants, and use a safer multimodal analgesic plan

Tramadol can precipitate delirium, constipation, falls and hyponatraemia in older adults, particularly after acute fracture. Pain still needs active treatment, but with safer regular analgesia, bowel regimen, mobilisation and review of reversible delirium drivers. Benzodiazepines would worsen delirium and falls. The pearl is that analgesic toxicity and undertreated pain can coexist, requiring careful substitution rather than therapeutic nihilism.

Reference: BNF; NICE CG103; STOPP/START v3