Bacteraemic pyelonephritis with polypharmacy — SCE Geriatric Medicine MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: C — Stop baclofen and obtain urgent renal advice about haemodialysis
Explanation lettering: C = shown as B · E = shown as C · B = shown as D · D = shown as E
A ignores profound accumulation at doses that appear low by usual adult standards. B targets a different receptor system. C treats a manifestation while leaving the renally retained toxin present. D is unsafe in severe encephalopathy. E is correct: stop baclofen immediately; severe toxicity in advanced renal failure is dialysable and requires urgent renal and airway assessment.
Reference: Baclofen 10 mg tablets SmPC: https://www.medicines.org.uk/emc/product/2594/smpc