Lewy body dementia with delirium and hallucinations — SCE Geriatric Medicine MCQ
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Correct answer: A — Continue treating reversible triggers and avoid antipsychotics unless severe distress or risk persists after de-escalation
Lewy body dementia carries a high risk of severe antipsychotic sensitivity and worsening parkinsonism. Management should prioritise reversible triggers, pain, environment and de-escalation; antipsychotics require great caution and specialist input when risk or distress persists. Haloperidol and olanzapine are particularly problematic. The pearl is that hallucinations in Lewy body dementia may fluctuate and often worsen during delirium.
Reference: NICE NG97; NICE NG71; NICE CG103