Meningococcal septicaemia — MRCPCH FOP MCQ
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Correct answer: E — High-flow oxygen, fluid bolus and immediate intravenous ceftriaxone
Shock with fever and purpuric non-blanching rash is meningococcal sepsis until proven otherwise, requiring immediate resuscitation and intravenous antibiotics. Lumbar puncture should not delay antibiotics and is unsafe in shock. Antihistamine is inappropriate because purpura and circulatory compromise are red flags. The pearl is that absence of neck stiffness does not exclude meningococcaemia.
Reference: NICE NG254 Suspected sepsis in under 16s; APLS