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Malaria chemoprophylaxis for West Africa — DTM&H MCQ

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HardMalariaMalaria chemoprophylaxis for West AfricaDTM&H

A healthy adult leaves in 48 hours for three weeks in rural Nigeria and prefers a regimen with the shortest post-travel course. Which chemoprophylaxis schedule best fits?

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Correct answer: D — Atovaquone-proguanil from 1–2 days before until seven days after exposure

The best answer is “Atovaquone-proguanil from 1–2 days before until seven days after exposure”. Atovaquone-proguanil is appropriate for chloroquine-resistant falciparum risk, can begin 1–2 days before entry and continues for seven days after leaving. Doxycycline requires four post-exposure weeks, mefloquine needs an earlier tolerance assessment, and primaquine cannot be used casually without G6PD assessment.

Reference: NaTHNaC TravelHealthPro: Malaria: https://travelhealthpro.org.uk/factsheet/52/malaria