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HIV PEP timing — DFSRH MCQ

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HardSTI diagnosis and managementHIV PEP timingDFSRH

A 24-year-old woman attends 50 hours after receptive condomless vaginal sex with a partner later disclosed to have untreated HIV. Baseline HIV test is negative and renal function is normal. What is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Start HIV PEP immediately and arrange follow-up testing

PEP is time-critical and should be started as soon as possible within 72 hours after a significant exposure. A negative baseline HIV test excludes established infection, not acquisition from this exposure. EC and STI testing are important but do not replace PEP.

Reference: BASHH/BHIVA HIV PEP Guideline; BASHH STI Testing Guidance