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Mycoplasma genitalium testing — DFSRH MCQ

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HardSTI diagnosis and managementMycoplasma genitalium testingDFSRH

A 35-year-old woman has persistent cervicitis after negative chlamydia and gonorrhoea NAATs and no PID signs. She completed doxycycline empirically 3 weeks ago. What is the most appropriate investigation?

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Correct answer: B — Mycoplasma genitalium NAAT with macrolide resistance testing if positive

Persistent cervicitis or urethritis after common STI tests should prompt consideration of Mycoplasma genitalium, ideally with resistance-guided management. Candida does not usually cause cervicitis. Negative chlamydia and gonorrhoea tests do not exclude other sexually transmitted causes.

Reference: BASHH Mycoplasma Genitalium Guideline