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Chlamydia treatment non-pregnant — DFSRH MCQ

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HardSTI diagnosis and managementChlamydia treatment non-pregnantDFSRH

A non-pregnant 22-year-old has uncomplicated vulvovaginal chlamydia confirmed by NAAT. She has no pelvic pain and takes no interacting medicines. What is the preferred treatment?

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Correct answer: E — Doxycycline 100 mg twice daily for 7 days with partner notification

The best answer is “Doxycycline 100 mg twice daily for 7 days with partner notification”. Doxycycline 100 mg twice daily for 7 days is first line for uncomplicated chlamydia in a non-pregnant adult. Partner notification, broader STI assessment and abstinence until treatment is completed are part of management. Single-dose azithromycin is no longer routine first line, while metronidazole and ceftriaxone target different infections.

Reference: BASHH, Chlamydia guideline with active treatment updates: https://www.bashh.org/resources/15/guidelines_chlamydia_2015