Addisonian crisis — SCE Acute Medicine MCQ
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Correct answer: E — Give intravenous hydrocortisone and isotonic saline immediately
This is adrenal crisis, and hydrocortisone plus rapid isotonic saline should be given immediately without waiting for cortisol confirmation. Oral mineralocorticoid is inadequate in shock and vomiting. Hyperkalaemia may improve with steroid and fluid resuscitation but should be treated if there are ECG changes. Hyponatraemia here reflects cortisol and aldosterone deficiency with volume depletion, not a reason for fluid restriction.
Reference: Society for Endocrinology adrenal crisis guidance, BNF