A 66-year-old woman has weight loss, mononeuritis multiplex and palpable purpura. Creatinine is 305 micromol/L with hematuria and red cell casts.

Question

A 66-year-old woman has weight loss, mononeuritis multiplex and palpable purpura. Creatinine is 305 micromol/L with hematuria and red cell casts. Chest CT shows multiple cavitating nodules, and PR3-ANCA is positive. Hepatitis B and C tests are negative. What is the most likely diagnosis?

Accepted Answer

Granulomatosis with polyangiitis

Answer

Cryoglobulinemic vasculitis

Answer

IgA vasculitis

Answer

Polyarteritis nodosa

Answer

Microscopic polyangiitis

ANCA-associated vasculitis — RCPSC IM MCQ

A 66-year-old woman has weight loss, mononeuritis multiplex and palpable purpura. Creatinine is 305 micromol/L with hematuria and red cell casts. Chest CT shows multiple cavitating nodules, and PR3-ANCA is positive. Hepatitis B and C tests are negative. What is the most likely diagnosis?