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Febrile neutropenia — RCPSC IM MCQ

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EasyInfectious DiseasesFebrile neutropeniaRCPSC IM

A 57-year-old woman receiving induction chemotherapy for acute myeloid leukemia presents with fever 38.7 C. Absolute neutrophil count is 0.1 x 10^9/L. Blood pressure is 104/68 mmHg and there is no focal source. Blood cultures have been drawn. What is the most appropriate management?

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Correct answer: B — Start empiric intravenous antipseudomonal beta-lactam therapy immediately

Febrile neutropenia is an emergency requiring prompt empiric broad-spectrum antibacterial therapy with antipseudomonal coverage after cultures are obtained.

Reference: Association of Medical Microbiology and Infectious Disease Canada febrile neutropenia guidance