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Non-alcoholic steatohepatitis with advanced fibrosis risk — RCPSC IM MCQ

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EasyGastroenterology/HepatologyNon-alcoholic steatohepatitis with advanced fibrosis riskRCPSC IM

A 56-year-old man with type 2 diabetes and obesity has ALT 86 U/L and AST 72 U/L for 18 months. He drinks 2 units of alcohol weekly. Ultrasound shows fatty liver. FIB-4 is 3.1 and platelet count is 132 x 10^9/L. What is the most appropriate next step?

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Correct answer: ERefer for fibrosis assessment with transient elastography or hepatology review

Metabolic risk factors with high FIB-4 and thrombocytopenia suggest advanced fibrosis risk and should prompt elastography or specialist assessment.

Reference: Canadian Association for the Study of the Liver MASLD/NAFLD resources