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Guillain-Barre syndrome — RCPSC IM MCQ

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ModerateNeurologyGuillain-Barre syndromeRCPSC IM

A 46-year-old man develops ascending weakness and paresthesias 10 days after gastroenteritis. Reflexes are absent. Forced vital capacity is 22 mL/kg. MRI spine is unrevealing. CSF is needed to support the diagnosis. What is the most appropriate investigation?

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Correct answer: DLumbar puncture for CSF protein and cell count

GBS is supported by albuminocytologic dissociation in CSF, though early CSF can be normal. Respiratory function should be monitored closely.

Reference: Canadian Neurological Sciences Federation neuromuscular guidance