A 34-year-old woman has autosomal dominant polycystic kidney disease and eGFR 74 mL/min/1.73 m2. Her mother died from subarachnoid hemorrhage at 49.

Question

A 34-year-old woman has autosomal dominant polycystic kidney disease and eGFR 74 mL/min/1.73 m2. Her mother died from subarachnoid hemorrhage at 49. She has no headache and blood pressure is controlled. She asks whether screening is indicated. What is the most appropriate investigation?

Accepted Answer

MR angiography of the intracranial circulation

Answer

Annual CT head without contrast

Answer

No screening because she is asymptomatic

Answer

Carotid duplex ultrasound

Answer

Routine lumbar puncture

Autosomal dominant polycystic kidney disease with aneurysm risk — RCPSC IM MCQ

A 34-year-old woman has autosomal dominant polycystic kidney disease and eGFR 74 mL/min/1.73 m2. Her mother died from subarachnoid hemorrhage at 49. She has no headache and blood pressure is controlled. She asks whether screening is indicated. What is the most appropriate investigation?