A 61-year-old woman with non-CF bronchiectasis has daily purulent sputum and three exacerbations requiring antibiotics in 12 months. CT confirms

Question

A 61-year-old woman with non-CF bronchiectasis has daily purulent sputum and three exacerbations requiring antibiotics in 12 months. CT confirms cylindrical bronchiectasis. Sputum cultures repeatedly grow Pseudomonas aeruginosa. She has completed airway clearance training and vaccinations are current. What is the most appropriate management?

Accepted Answer

Specialist-directed long-term inhaled antipseudomonal antibiotic therapy

Answer

Long-term oral corticosteroid therapy

Answer

Stop airway clearance because cultures are positive

Answer

Lung transplant referral as the first escalation

Answer

Empiric tuberculosis treatment without cultures

Bronchiectasis with chronic Pseudomonas infection — RCPSC IM MCQ