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Oligometastatic lung cancer staging — SCE Respiratory MCQ

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HardLung CancerOligometastatic lung cancer stagingSCE Respiratory

A 60-year-old man has a 4 cm right lower-lobe NSCLC and PET-positive adrenal lesion. The adrenal lesion is the sole possible metastatic site. What is the most appropriate investigation?

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Correct answer: E — Tissue sampling of the adrenal lesion if it would alter curative treatment intent

A solitary extrathoracic PET-positive lesion should be confirmed histologically when the result would change curative versus palliative intent. Proceeding to surgery without clarification risks futile treatment, while assuming benign disease risks undertreatment of metastasis. Hormonal testing may assess adrenal function but does not stage lung cancer.

Reference: NICE NG122